Platelet Thrombosthenin: Subcellular Localization and Function*
نویسندگان
چکیده
منابع مشابه
Platelet thrombosthenin: subcellular localization and function.
Thrombosthenin, an immunologically distinct contractile protein was isolated in relatively pure form from human platelets. The protein, which was of high molecular weight appeared to be composed of multiple polypeptide subunits, probably polymeric in nature.Thrombosthenin had magnesium-dependent ATPase activisty, releasing an average of 3 mug phosphorus per mg protein in 30 min. After the addit...
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Purified human platelets were found to contain a collagenase inhibitor that is immunologically, functionally, and chromatographically identical to that produced by human skin fibroblasts. None of the other formed elements of the blood (erythrocytes, granulocytes, mononuclear cells) possessed detectable quantities of this protein. Virtually all the collagenase inhibitor contained within platelet...
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Four platelet proteins are secreted by platelets during the release reaction: platelet factor 4 (PF4).1 $-thromboglobulin ( 9TG). platelet-derived growth factor (PDGF). and fibrinogen. The characteristics of release of these proteins and 14Cserotonin (14C-5HT) were studied and compared with secretion of acid hydrolases as described by others.’ Distinct differences were found between the release...
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Four platelet proteins are secreted by platelets during the release reaction: platelet factor 4 (PF4).1 $-thromboglobulin ( 9TG). platelet-derived growth factor (PDGF). and fibrinogen. The characteristics of release of these proteins and 14Cserotonin (14C-5HT) were studied and compared with secretion of acid hydrolases as described by others.’ Distinct differences were found between the release...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1967
ISSN: 0021-9738
DOI: 10.1172/jci105630